Sanford Burnham Prebys is a preeminent, independent biomedical research institute dedicated to understanding human biology and disease, and advancing scientific discoveries to profoundly impact human health.

Summary:

The Huang laboratory has a Postdoctoral Associate position available!!!

Dr. Timothy Huang's laboratory focuses on understanding how mutations in cell surface proteins such as TREM2 and SORLA can alter neuronal and microglial function. Recent work from our group established a role for SORLA in protecting synaptic function in the presence of Aß (J Exp Med 214: 3669, 2017) as well as enhancing neurite outgrowth (J Neurosci 40: 5908, 2020). The Huang lab also established an ESC-based human microglial modeling platform to determine how AD-related mutations in TREM2 and SORLA can affect microglia behavior and function (J Exp Med 217(12): e20200474, 2020). The Huang lab is currently using a combination of mouse genetics, biochemistry, cell biology, proteomics, and high throughout sequencing technologies to characterize molecular pathways associated with genes such as TREM2 and SORLA.

The lab is looking for a highly motivated postdoctoral associate to study the role of genetic sporadic risk factors in Alzheimer’s disease (AD) on triggering and exacerbating AD onset.

TO APPLY: Interested candidates should apply online to the SBP career site by submitting one PDF document with a cover letter, CV, references and list of any publications or accomplishments.

Primary Responsibilities:

• Independently design and perform experiments and procedures with high degree of complexity, demonstrating increasing expertise with a wide range of techniques
• Demonstrate flexibility in adapting methods and skills according to evolving project priorities
• Provide independent experimental design and planning
• Be able to analyze and interpret data from different sources and draw relevant conclusions
• Demonstrate knowledge in relevant specialized disciplines
• Be able to present results at internal and external meetings
• Accurately document experiments
• Contribute to writing of reports and manuscripts with increasing responsibility over time
• Work collaboratively across lab functions and train other junior lab staff as needed

Requirements:

• Ph.D. and/or M.D. with background in neuroscience, genetics, cellular and/or molecular biology.

Knowledge, Skills and/or Abilities:

• The ability to work independently and to handle multiple projects and deadlines
• Demonstrated ability to work in an interactive and collaborative team
• Excellent presentation, verbal, and written communication skills
• Possess strong attention to detail, analytical, time management, organizational, and interpersonal skills
• Embody the Institute's core values of Commitment, Collaboration, Communication, Community and Compassion

COMPENSATION:

The expected compensation for this position is between $68,016.00 - $75,004.80/year commensurate with experience.

Sanford Burnham Prebys Medical Discovery Institute is an Equal Opportunity employer – M/F/Veteran/Disability – committed to the hiring, advancement and fair treatment of all individuals. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, or any other protected status as designated by federal, state or local law. For additional information about your rights as an applicant, click HERE.

As part of this commitment, Sanford Burnham Prebys Medical Discovery Institute will ensure that persons with disabilities are provided reasonable accommodations for the hiring process. If a reasonable accommodation is needed, please contact our HR Partners at 858 646 3100 Ext 5127 or via e-mail at accomodations@sbpdiscovery.org.